General Information
Growth-differentiation factor 15 (GDF15), inozivikanwawo seMIC-1, inhengo yakavanzwa yekuchinja kwekukura (TGF) -β superfamily, sechinhu chinorwisa antihypertrophic regulatory factor mumoyo.GDF-15 / GDF15 haina kuratidzwa mumoyo wevanhu vakuru asi inokurudzirwa maererano nemamiriro ezvinhu anokurudzira hypertrophy uye dilated cardiomyopathy uye inoratidzwa zvakanyanya muchiropa.GDF-15 / GDF15 ine basa rekugadzirisa nzira dzekuzvimba uye dzeapoptotic mumatishu akakuvara uye panguva yezvirwere.GDF-15 / GDF15 inogadzirwa se precursor molecules inogadziriswa panzvimbo ye dibasic cleavage kuti ibudise C-terminal domains ine chimiro chechimiro che 7 conserved cysteines muprotein yakakura.GDF-15 / GDF15 overexpression ichibva kune yakawedzera erythroid compartment inobatsira kune iron yakawandisa muthalassemia syndromes nekudzivisa hepcidin kutaura.
Pair Recommendation | CIA (Kutora-Kuonekwa): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
Kuchena | > 95%, yakatarwa neSDS-PEJI |
Buffer Formulation | PBS, pH7.4. |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
GDF-15 | AB0038-1 | 3A2-1 |
AB0038-2 | 23F1-5 | |
AB0038-3 | 6C1-9 | |
AB0038-4 | 4D5-8 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Wollert KC , Kempf T , Peter T , et al.Prognostic Value of Growth-Differentiation Factor-15 muVarwere Vasina-ST-Elevation Acute Coronary Syndrome[J].Circulation, 2007, 115(8):962-971.
2.Kempf T, Haehling SV, Peter T, et al.Prognostic utility yekukura differentiation factor-15 muvarwere vane chirwere chemoyo chisingaperi.[J].Nyaya yeAmerican College yeCardiology, 2007, 50 (11): 1054-1060.