General Information
IGFBP1, inozivikanwawo se IGFBP-1 uye insulin-yakafanana nekukura-inosunga mapuroteni 1, inhengo ye-insulin-yakafanana nekukura-inosunga mapuroteni mhuri.IGF inosunga mapuroteni (IGFBPs) mapuroteni e24 kusvika ku45 kDa.Ese maIGFBP matanhatu anogovera 50% homology uye ane anosunga affinities eIGF-I neIGF-II panguva imwechete yehukuru sematanho ane iyo IGF-IR.IGF-inosunga mapuroteni anowedzera hafu yehupenyu hweIGFs uye akaratidzwa kuti anogona kurambidza kana kukurudzira kukura-kukurudzira mhedzisiro yeIGFs pane cell tsika.Ivo vanoshandura kupindirana kweIGFs ne cell yavo yepamusoro receptors.IGFBP1 ine IGFBP domain uye thyroglobulin type-I domain.Inosunga zvose insulin-sekukura zvinhu (IGFs) I uye II uye inotenderera muplasma.Kusungirirwa kweprotein iyi kunowedzera hafu yehupenyu hweIGF uye inoshandura kuwirirana kwavo ne cell surface receptors.
Pair Recommendation | CIA (Kutora-Kuonekwa): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
Kuchena | > 95% sezvakatemwa neSDS-PAGE. |
Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Bioantibody | Clinically Kuongororwa Nyaya | Total | |
Positive | Negative | ||
Positive | 35 | 0 | 35 |
Negative | 1 | 87 | 88 |
Total | 36 | 87 | 123 |
Zvakananga | 100% | ||
Sensitivity | 97% |
Product Name | Katsi.Aihwa | Clone ID |
IGFBP-1 | AB0028-1 | 4H6-2 |
AB0028-2 | 4C2-3 | |
AB0028-3 | 2H11-1 | |
AB0028-4 | 3G12-11 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Rutanen EM .Insulin-yakafanana nekukura chinhu chinosunga mapuroteni 1: US 1996.
2.Harman, S, Mitchell, nevamwe.Serum Levels yeInsulin-Kufanana neKukura Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, uye Prostate-Specific Antigen se Predictors yeClinical Prostate Cancer [J].Nyaya yeClinical Endocrinology & Metabolism, 2000.