Anti-munhu MMP-3 Antibody, Mouse Monoclonal
Product details
General Information
Matrix metallopeptidase 3 (yakadimburirwa seMMP3) inozivikanwawo se stromelysin 1 uye progelatinase.MMP3 inhengo yemhuri yematrix metalloproteinase (MMP) ine nhengo dzinenge dzichibatanidzwa mukuparara kwe extracellular matrix mune zvakajairika physiological process, senge embryonic development, kuberekana, kugadziridza matishu, uye maitiro ezvirwere anosanganisira arthritis uye metastasis.Seyakavanzwa zinc-inotsamira endopeptidase, MMP3 inoita mabasa ayo kunyanya mu extracellular matrix.Iri puroteni rinoitwa neaviri makuru endogenous inhibitors: alpha2-macroglobulin uye tishu inhibitors ye metalloproteases (TIMPs).MMP3 inobata basa repakati mukusvibisa collagen mhando II, III, IV, IX, uye X, proteoglycans, fibronectin, laminin, uye elastin.Zvakare, MMP3 inogona kushanda mamwe maMMP akadai seMMP1, MMP7, uye MMP9, ichipa MMP3 yakakosha mukubatanidza matishu kugadzirisa.Dysregulation yeMMPs yakabatanidzwa muzvirwere zvakawanda zvinosanganisira arthritis, chironda chisingaperi, encephalomyelitis, uye kenza.Synthetic kana natural inhibitors yeMMPs inoguma nekudzivirirwa kwemetastasis, nepo kumusoro-mutemo weMMPs uchitungamira kukuwedzera cancer cell invasion.
Properties
| Pair Recommendation | CIA (Kutora-Kuonekwa): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4 |
| Kuchena | > 95%, yakatarwa neSDS-PEJI |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Kuenzanisa Kwemakwikwi
Order Information
| Product Name | Katsi.Aihwa | Clone ID |
| MMP-3 | AB0025-1 | 11G11-6 |
| AB0025-2 | 8A3-9 | |
| AB0025-3 | 5B9-4 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
Citations
1.Yamanaka H , Matsuda Y , Tanaka M , et al.Serum matrix metalloproteinase 3 sekufanotaura kwechidimbu chekuparadzwa kwekubatana mukati memwedzi mitanhatu mushure mekuyerwa, muvarwere vane rheumatoid arthritis yepakutanga[J].Arthrits & Rheumatism, 2000, 43(4):852–858.
2.Hattori Y , Kida D , Kaneko A .Yakajairika serum matrix metalloproteinase-3 mazinga anogona kushandiswa kufanotaura kuregererwa kwekiriniki uye yakajairika basa remuviri kune varwere vane rheumatoid arthritis [J].Clinical Rheumatology, 2018.
