General Information
Pepsinogen I, iyo inotangira pepsin, inogadzirwa negastric mucosa uye inosunungurwa mugastric lumen uye peripheral circulation.Pepsinogen ine cheni imwe chete yepolypeptide ye375 amino acids ine avhareji yehuremu hwe42 kD.PG I (isoenzyme 1-5) inovanzwa kunyanya nemasero makuru mu fundic mucosa, nepo PG II (isoenzyme 6-7) yakavanzwa ne pyloric glands uye proximal duodenal mucosa.
Precursor inoratidza huwandu hwemaseru emudumbu epamusoro pamwe nemaseru eglandu, uye inotarisisa gastric atrophy zvisina kunanga.Ivo zvakare vakagadzikana zvinoshamisa nekuti vanoita mabasa avo pasi pemamiriro akaomarara aripo muhurongwa hwekugaya.Iyo atrophy ye corpus mucosa inotungamira kune yakaderera synthesis ye pepsinogen I uye nokudaro yakaderera kuburitswa muserum.Serum pepsinogen I inoratidza basa uye mamiriro egastric mucosa.
Pair Recommendation | CIA (Kutora-Kuonekwa): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
Kuchena | > 95%, yakatarwa neSDS-PEJI |
Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
PGI | AB0005-1 | 1C1-3 |
AB0005-2 | 1E3-1 | |
AB0005-3 | 1G7-3 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Sipponen P , Ranta P , Helske T , et al.Serum mazinga e amidated gastrin-17 uye pepsinogen I muatrophic gastritis: kuongorora nyaya-control study.[J].Scandinavian Journal yeGastroenterology, 2002, 37(7):785-791.
2.Mangla JC , Schenk EA , Desbaillets L , et al.Pepsin secretion, pepsinogen, uye gastrin muBarrett's esophagus '.Clinical uye morphological maitiro[J].Gastroenterology, 1976, 70(5 PT.1):669-676.