General Information
Preeclampsia (PE) idambudziko rakakomba repamuviri rinoratidzwa nehypertension uye proteinuria mushure memavhiki makumi maviri ekuzvitakura.Preeclampsia inoitika mu3-5 % yenhumbu uye inokonzeresa kuwanda kwekufa kwaamai nevemwana kana mbereko nekurwara.Kuratidzwa kwekiriniki kunogona kusiyana kubva kunyoro kusvika kune yakaoma mafomu;preeclampsia ichiri chimwe chezvikonzero zvinotungamira zvekurwara nekufa kwe fetal uye amai.
Preeclampsia inoratidzika kunge inokonzerwa nekusunungurwa kweangiogenic zvinhu kubva pa placenta iyo inokonzera endothelial dysfunction.Serum mazinga ePlGF (placental growth factor) uye sFlt-1 (soluble fms-senge tyrosine kinase-1, inozivikanwawo sesoluble VEGF receptor-1) inoshandurwa muvakadzi vane preeclampsia.Zvakare, mazinga ekutenderera ePLGF nesFlt-1 anogona kusarura nhumbu yakajairika kubva kupreeclampsia kunyangwe zviratidzo zvekiriniki zvisati zvaitika.Mumimba yakajairika, pro-angiogenic factor PlGF inowedzera mukati mematrimester maviri ekutanga uye inodzikira sezvo nhumbu inokura kusvika panguva.Kusiyana neizvi, mazinga e-anti-angiogenic factor sFlt-1 anoramba akagadzikana panguva yekutanga uye yepakati matanho ekuzvitakura uye anowedzera zvishoma kusvika panguva.Muvakadzi vanoita preeclampsia, sFlt-1 mazinga akawanikwa akakwira uye mazinga ePLGF akawanikwa akaderera pane akajairika pamuviri.
Pair Recommendation | CIA (Kutora-Kuonekwa): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
Kuchena | > 95% sezvakatemwa neSDS-PAGE. |
Buffer Formulation | PBS, pH7.4. |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
PLGF | AB0036-1 | 7G1-2 |
AB0036-2 | 5D9-3 | |
AB0036-3 | 5G7-1 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Brown MA, Lindheimer MD, de Swiet M, et al.Kurongeka uye kuongororwa kwehutachiona hwehutachiona hwekuzvitakura: chirevo kubva kuInternational Society yeChidzidzo cheHypertension muKubata (ISSHP).Hypertens Pregnancy 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al.Pre-eclampsia: pathophysiology, kuongororwa, uye manejimendi.Vasc Health Risk Manag 2011;7:467-474.