General Information
Retinol-binding protein 4 (RBP4) ndiyo chaiyo inotakura retinol (inozivikanwawo sevhitamini A), uye ine basa rekushandura retinol isina kugadzikana uye isina kunyungudika mumushonga wemvura mune yakagadzikana uye yakanyungudika yakaoma muplasma kuburikidza nekubatana kwavo kwakasimba.Senhengo ye lipocalin superfamily, RBP4 ine β-barrel structure ine mhango yakanyatsotsanangurwa inovanzwa kubva pachiropa, uye zvakare inopa retinol kubva muzvitoro zvechiropa kusvika kune peripheral tissues.Muplasma, RBP4-retinol complex inosangana ne transthyretin (TTR), uye kusunga uku kwakakosha pakudzivirira RBP4 kubuda kuburikidza neitsvo glomeruli.RBP4 inoratidzwa kubva kune ectopic sosi inoburitsa retinol kumaziso, uye kushomeka kwayo kunokanganisa kuona kwehusiku zvakanyanya.Munguva ichangopfuura, RBP4 seadipokine, inowanikwa inoratidzwa mune adipose tissue uye yakabatana nekurema, insulin resistance (IR) uye rudzi rwe 2 chirwere cheshuga (T2DM).
Pair Recommendation | CIA (Kutora-Kuonekwa): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
Kuchena | > 95% sezvakatemwa neSDS-PAGE. |
Buffer Formulation | PBS, pH7.4. |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
RBP4 | AB0032-1 | 9D11-8 |
AB0032-2 | 3C8-1 | |
AB0032-3 | 3D4-1 | |
AB0032-4 | 1C6-1 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.Retinol inosunga mapuroteni 4 muvanhu: hukama ne insulin kuramba, kuzvimba, uye mhinduro kune pioglitazone.[J].J Clin Endocrinol Metab(7):2590-2597.
2.Haider DG , Karin S , Gerhard P , et al.Serum retinol-binding protein 4 inodzikiswa mushure mekuderera kwehuremu muvanhu vakafuta zvakanyanya.[J].Nyaya yeClinical Endocrinology & Metabolism (3): 1168-71.