General Information
Hormone yepabonde inosunga globulin (SHBG) inonzi glycoprotein inenge 80-100 kDa;ine hukama hwepamusoro hwe17 beta-hydroxysteroid hormones yakadai se testosterone uye estradiol.SHBG
kusungirirwa muplasma kunodzorwa, pakati pezvimwe zvinhu, androgen/estrogen chiyero, thyroid mahormone, insulin uye chikafu zvinhu.Ndiyo inonyanya kukosha mapuroteni ekutakura eestrogens uye androgens muropa reperipheral.SHBG kusungirirwa ndicho chinhu chikuru chinogadzirisa kugoverwa kwavo pakati peprotein-bound and free states.Plasma SHBG kutariswa kuri
yakakanganiswa nehuwandu hwezvirwere zvakasiyana-siyana, maitiro akakwirira anowanikwa mu hyperthyroidism, hypogonadism, androgen insensitivity uye hepatic cirrhosis muvarume.Kudzika kwakadzika kunowanikwa mu myxoedema, hyperprolactinemia uye syndromes yekunyanyisa uyerogen basa.Kuyera kweSHBG kunobatsira mukuongororwa kwekusagadzikana kwakapfava kwe androgen metabolism uye kunogonesa kuzivikanwa kweavo vakadzi vane hirsutism avo vanogona kupindura kune estrogen therapy.
Pair Recommendation | CIA (Kutora-Kuonekwa): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
Kuchena | > 95%, yakatarwa neSDS-PEJI |
Buffer Formulation | PBS, pH7.4. |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
SHBG | AB0030-1 | 3A10-5 |
AB0030-2 | 3E10-1 | |
AB0030-3 | 3D8-2 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1. Selby C. Hormone yepabonde inosunga globulin: mavambo, basa uye kukosha kwekliniki.Ann Clin Biochem 1990;27:532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Clinical utility yehomoni yebonde inosunga globulin kuyerwa.Horm Res 1996;45(3-5):148-155.