General Information
Human epidermal growth factor receptor 2 (HER2), inozivikanwawo seErbB2, NEU, uye CD340, imhando I membrane glycoprotein uye ndeye epidermal growth factor (EGF) receptor mhuri.HER2 protein haigone kusunga zvinhu zvekukura nekuda kwekushaikwa kwe ligand binding domain yayo uye yakazvivharira zvinomiririra.Nekudaro, HER2 inoumba heterodimer nedzimwe ligand-yakasungwa EGF receptor nhengo dzemhuri, saka inodzikamisa ligand kusunga uye inosimudzira kinase-mediated activation yemamorekuru ekudzika.HER2 inobata basa rakakosha mukusimudzira, kuwanda kwesero uye kusiyanisa.HER2 gene inonzi inobatana nehuipi uye kusaziva zvakanaka mune dzakawanda carcinomas, kusanganisira zamu, prostate, ovarian, kenza yemapapu uye zvichingodaro.
Pair Recommendation | CIA (Kutora-Kuonekwa): 14-2~ 15-6 15-6~ 2-10 |
Kuchena | > 95%, yakatarwa neSDS-PEJI |
Buffer Formulation | PBS, pH7.4. |
Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Product Name | Katsi.Aihwa | Clone ID |
Her2 | AB0078-1 | 14-2 |
AB0078-2 | 15-6 | |
AB0078-3 | 2-10 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
1.Krawczyk N, nevamwe.(2009) HER2 chimiro pane anoramba achiparadzira bundu maseru mushure meadjuvant therapy inogona kusiyana neyekutanga HER2 chimiro pane yekutanga bundu.Anticancer Res.29(10): 4019-24.