Anti- munhu CHI3L1 Antibody, munhu Monoclonal
Product details
General Information
Chitinase-3-yakafanana neprotein 1 (CHI3L1) inonzi heparin-binding glycoprotein iyo kutaura kwayo kunobatanidza nevascular smooth muscle cell migration.CHI3L1 inoratidzwa pamazinga akakwirira mune postconfluent nodular VSMC tsika uye pamwero wakaderera mune subconfluent proliferating tsika.CHI3L1 is a tissue-restricted, chitin-binding lectin uye nhengo ye glycosyl hydrolase mhuri 18. Kusiyana nemamwe akawanda monocyto / macrophage markers, kutaura kwayo hakusipo mu monocytes uye yakasimba inokonzerwa munguva dzekupedzisira dzekusiyanisa macrophage evanhu.Akakwira mazinga eCHI3L1 anosanganisirwa nekusawirirana kunoratidza kuwedzera kwekubatanidza matishu kuchinja, senge rheum atoid, arthritis, osteoarthritis, scleroderma, uye cirrhosis yechiropa, asi inogadzirwa mucartilage kubva kune vekare vanopa kana varwere vane osteoarthritis.CHI3L1 inoratidzwa zvisina kujairika muhippocampus yezvidzidzo zvine schizophrenia uye inogona kubatanidzwa mukupindura kweserura kune dzakasiyana siyana zviitiko zvezvakatipoteredza izvo zvinonzi zvinowedzera njodzi yeschizophrenia.
Properties
| Pair Recommendation | CIA (Kutora-Kuonekwa): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| Kuchena | > 95%, yakatarwa neSDS-PEJI |
| Buffer Formulation | PBS, pH7.4 |
| Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Nekuchengetedza kwenguva refu, ndapota aliquot uye chengeta.Dzivisa kudzokororwa nechando uye kunyunguduka kutenderera. |
Kuenzanisa Kuongorora
| Bioantibody | chirwere chakaongororwa nekliniki | Total | |
| positive | Negative | ||
| positive | 46 | 3 | 49 |
| Negative | 4 | 97 | 101 |
| Total | 50 | 100 | 150 |
| evaluation index | kunzwa | specificity | kururama |
| 92% | 97% | 95% | |
Order Information
| Product Name | Katsi.Aihwa | Clone ID |
| CHI3L1 | AB0031-1 | 1G11-14 |
| AB0031-2 | 2E4-2 | |
| AB0031-3 | 3A12-1 | |
| AB0031-4 | 13F3-1 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
Citations
1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al.Yakakwira kutenderera kweserum acute-phase protein YKL-40 (chitinase 3-seprotein 1) chiratidzo chekufutisa uye insulin kuramba muvana vasati vasununguka[J].Metabolism-clinical & Experimental, 2012, 61(4):562-568.
2.Yu-Huan M , Li-Ming T , Jian-Ying LI , et al.Ongororo pakushandiswa kweserum chitinase-3-seprotein 1, alpha-fetoprotein uye kuonekwa kweferritin pakuongorora hepatocellular carcinoma[J].Practical Preventive Medicine, 2018.
