Anti-munhu TIMP1 Antibody, Mouse Monoclonal
Product details
General Information
TIMP metallopeptidase inhibitor 1, inozivikanwawo seTIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating chiitiko, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is natural inhibitors of the metalloproteinase matrix metalloproteinases. inobatanidzwa mukuderedzwa kweiyo extracellular matrix.TIMP-1/TIMP1 inowanikwa mu fetal uye vanhu vakuru tishu.Mazinga akakwirira anowanikwa mumapfupa, mapapu, ovary uye chibereko.Inoomesa nemetalloproteinases uye inoamisa zvisingachinjiki nekusunga kune yavo catalytic zinc cofactor.TIMP-1/TIMP1 inopindirana erythropoiesis in vitro;asi, kusiyana neIL-3, ndeyemhando-yakananga, inokurudzira kukura uye kusiyanisa kwevanhu chete uye murine erythroid progenitors.Mukuwedzera kune basa rayo rekudzivirira rinopesana nevakawanda veMMPs vanozivikanwa, puroteni inokwanisa kukurudzira kuwedzera kwesero mumhando dzakasiyana-siyana dzemasero, uye inogonawo kuva ne-anti-apoptotic function.Kudhindwa kweiyi proteinencoding gene inogoneka zvakanyanya mukupindura kune akawanda cytokines nemahomoni.Pamusoro pezvo, kutaura kunobva kune mamwe asi asiri ese asingashande maX chromosomes anoratidza kuti iyi gene inactivation ndeye polymorphic muvakadzi vevanhu.Iyi encoding gene iri mukati me intron 6 ye synapsin I gene uye inonyorerwa nenzira yakapesana.Inoomesa nemetalloproteinases uye inoamisa zvisingachinjiki nekusunga kune yavo catalytic zinc cofactor.TIMP-1/TIMP1 Inozivikanwa ichiita paMMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 uye MMP-16.
Properties
| Pair Recommendation | CIA (Kutora-Kuonekwa): 1D5-5 ~ 3G11-6 1D12-2 ~ 1G3-7 |
| Kuchena | > 95% sezvakatemwa neSDS-PAGE. |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Chengetedza pasi pemamiriro ekudzivirira pa -20 ℃ kusvika -80 ℃ paunogamuchira. Recommended kune aliquot the protein muzvikamu zvidiki kuti chengetedzo yakakwana. |
Kuenzanisa Kwemakwikwi
Order Information
| Product Name | Katsi.Aihwa | Clone ID |
| TIMP1 | AB0034-1 | 1D5-5 |
| AB0034-2 | 1D12-2 | |
| AB0034-3 | 1G3-7 | |
| AB0034-4 | 3G11-6 |
Ongorora: Bioantibody inogona kugadzirisa huwandu maererano nezvaunoda.
Citations
1.Barylski M , Kowalczyk E , Szadkowska I , et al.[Tissue inhibitor ye metalloproteinases[J].Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.
2.Hayakawa T , Yamashita K , Tanzawa K , et al.Kukura-kukurudzira basa retishu inhibitor ye metalloproteinases-1 (TIMP-1) yeakasiyana siyana maseru Chinhu chitsva chinogona kukura muserum[J].Tsamba dzeFEBS, 1992, 298.
3.Haider DG , Karin S , Gerhard P , et al.Serum retinol-binding protein 4 inodzikiswa mushure mekuderera kwehuremu muvanhu vakafuta zvakanyanya.[J].Nyaya yeClinical Endocrinology & Metabolism (3): 1168-71.
